SCHEMBL22028548

SCHEMBL22028548

CC(O)CCCC(CCCC(C)O)(C(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.41
ACACA Q13085 1/20 0.41
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.34
TP53 P04637 1/20 0.33
ARG1 P05089 1/20 0.32
ARG2 P78540 1/20 0.32
GPR84 Q9NQS5 3/20 0.31
FFAR1 O14842 1/20 0.31
BLM P54132 1/20 0.30
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22028557 0.96 ACACB (0.47) ACACBACACAALDH1A1MAPTTP53
SCHEMBL22028550 0.88 ACACB (0.38) ACACBACACAALDH1A1TP53GABRP
SCHEMBL20550429 0.79 ACACB (0.44) ACACBACACAALDH1A1MAPTTP53
SCHEMBL3594255 0.79 BLM (0.52) ACACBACACABLMGABRR1CYP1A2
SCHEMBL9955621 0.77 ACACB (0.47) ACACBACACAARG1ARG2GPR84
SCHEMBL9955760 0.77 ACACB (0.47) ACACBACACAARG1ARG2GPR84
SCHEMBL22028556 0.77 ACACB (0.47) ACACBACACAMAPTGPR84FFAR1
SCHEMBL9955572 0.77 ACACB (0.47) ACACBACACAARG1ARG2GPR84
SCHEMBL9954778 0.77 ACACB (0.47) ACACBACACAARG1ARG2GPR84
SCHEMBL9953951 0.77 ACACB (0.47) ACACBACACAARG1ARG2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3491044-B1 METHOD OF REGIOSELECTIVE SYNTHESIS OF POLYESTERS FROM ASYMMETRIC DIOLS VERSALIS SPA (IT) 2020-08-26 EP disclosed
US-20200181319-A1 METHOD OF REGIOSELECTIVE SYNTHESIS OF POLYESTERS FROM ASYMMETRIC DIOLS VERSALIS S.P.A. (IT) 2020-06-11 US disclosed