Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23175990 | 0.92 | CHRM4 (0.47) | CHRM4CHRM1CHRM2GAATP53 | |
| SCHEMBL22030609 | 0.91 | CHRM4 (0.54) | CHRM4CHRM1CHRM2GAATP53 | |
| SCHEMBL17020250 | 0.90 | CHRM4 (0.56) | CHRM4CHRM1CHRM2GAATP53 | |
| SCHEMBL22031184 | 0.88 | CHRM4 (0.52) | CHRM4CHRM1CHRM2GAATP53 | |
| SCHEMBL15618723 | 0.88 | CHRM4 (0.56) | CHRM4CHRM1CHRM2GAATP53 | |
| SCHEMBL15618794 | 0.88 | CHRM4 (0.56) | CHRM4CHRM1CHRM2GAATDP1 | |
| SCHEMBL21837253 | 0.87 | CHRM4 (0.55) | CHRM4CHRM1CHRM2GAATP53 | |
| SCHEMBL15630273 | 0.87 | CHRM1 (0.64) | CHRM4CHRM1CHRM2GAATP53 | |
| SCHEMBL21837267 | 0.85 | CHRM4 (0.53) | CHRM4CHRM1CHRM2GAATP53 | |
| SCHEMBL18825073 | 0.84 | CHRM4 (0.53) | CHRM4CHRM1CHRM2GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220298133-A1 | OXIME COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | NXERA PHARMA UK LIMITED (GB) | 2022-09-22 | — | — | US | disclosed |
| US-11208396-B2 | Oxime compounds as agonists of the muscarinic M1 and/or M4 receptor | HEPTARES THERAPEUTICS LIMITED (GB) | 2021-12-28 | — | — | US | disclosed |
| US-20200165220-A1 | OXIME COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | NXERA PHARMA UK LIMITED (GB) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165220-A1 | OXIME COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM1 1/4885CHRM2 2/4885 |
| US-20220298133-A1 | OXIME COMPOUNDS AS AGONISTS OF THE MUSCARINIC M1 AND/OR M4 RECEPTOR | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM1 1/4885CHRM2 2/4885 |
| US-11208396-B2 | Oxime compounds as agonists of the muscarinic M1 and/or M4 receptor | CHRM1, CHRM2, CHRM4 | CHRM4 3/4885CHRM1 1/4885CHRM2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.