Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2203176

CC[C@@H](C(=O)O)C1CCCNC1.O=C(O)C(F)(F)F

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 3/20 0.60
CPB2 Q96IY4 3/20 0.60
SLC6A1 P30531 2/20 0.37
SLC6A11 P48066 1/20 0.37
TSHR P16473 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SLC6A13 Q9NSD5 1/20 0.37
HRH4 Q9H3N8 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
CYP2D6 P10635 1/20 0.33
IRAK4 Q9NWZ3 4/20 0.32
DPP8 Q6V1X1 2/20 0.32
DPP7 Q9UHL4 2/20 0.32
DPP4 P27487 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2202166 1.00 CPN1 (0.60) CPN1CPB2SLC6A1SLC6A11TSHR
Trifluoroacetic Acid SCHEMBL27750059 1.00 CPN1 (0.60) CPN1CPB2SLC6A1SLC6A11TSHR
SCHEMBL7689250 0.91 CPN1 (0.71) CPN1CPB2SLC6A1SLC6A11TSHR
Hydrochloric Acid SCHEMBL22443992 0.90 CPN1 (0.69) CPN1CPB2SLC6A1SLC6A11TSHR
SCHEMBL27465384 0.81 CPN1 (0.56) CPN1CPB2SLC6A1SLC6A11SLC6A13
Bromide SCHEMBL27157552 0.80 CPN1 (0.54) CPN1CPB2SLC6A1SLC6A11SLC6A13
Bromide SCHEMBL27157473 0.80 CPN1 (0.54) CPN1CPB2SLC6A1SLC6A11SLC6A13
SCHEMBL2354438 0.75 CPN1 (1.00) CPN1CPB2SLC6A1SLC6A11TSHR
SCHEMBL1336664 0.75 CPN1 (0.53) CPN1CPB2SLC6A1SLC6A11TSHR
SCHEMBL28377764 0.74 CPN1 (0.44) CPN1CPB2TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977349-B2 Substituted quinolones III AICURIS GMBH & CO. KG (DE) 2011-07-12 US disclosed