SCHEMBL220322

SCHEMBL220322

CCCC(Cl)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27472425 0.82
SCHEMBL6703853 0.79
SCHEMBL11712016 0.79
SCHEMBL788681 0.78
SCHEMBL27570495 0.76
SCHEMBL28109637 0.76
SCHEMBL2003680 0.73
SCHEMBL483757 0.73
SCHEMBL11717122 0.73
Ammonia Solution, Strong SCHEMBL10424689 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768307-B1 OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE BIKAM PHARMACEUTICALS INC (US) 2020-03-18 EP disclosed
EP-3100723-B1 OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE BIKAM PHARMACEUTICALS INC (US) 2019-06-12 EP disclosed
EP-2785178-B1 OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE BIKAM PHARMACEUTICALS INC (US) 2019-05-01 EP disclosed
US-20190023649-A1 Opsin-Binding Ligands, Compositions and Methods of Use BIKAM PHARMACEUTICALS, INC. (US) 2019-01-24 US disclosed
EP-2720539-B1 OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE BIKAM PHARMACEUTICALS INC (US) 2018-10-24 EP disclosed
US-10040749-B2 Opsin-binding ligands, compositions and methods of use BIKAM PHARMACEUTICALS INC. (US) 2018-08-07 US disclosed
EP-3204009-A1 HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES BioMarin Pharmaceutical Inc. (US) 2017-08-16 EP disclosed
US-20170137398-A1 OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE BIKAM PHARMACEUTICALS, INC. (US) 2017-05-18 US disclosed
WO-2016057834-A9 HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES BIOMARIN PHARMACEUTICAL INC. (US) 2017-04-13 WO disclosed
US-20170037024-A1 Opsin-Binding Ligands, Compositions and Methods for Use BIKAM PHARMACEUTICALS, INC. (US) 2017-02-09 US disclosed
EP-0941086-A1 NITROSATED AND NITROSYLATED PHOSPHODIESTERASE INHIBITOR COMPOUNDS, COMPOSITIONS AND THEIR USES Nitromed, Inc. (US) 1999-09-15 EP disclosed
US-5874437-A Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses NITROMED, INC. (US) 1999-02-23 US disclosed
US-5824669-A Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders NITROMED, INC. (US) 1998-10-20 US disclosed
WO-1998019672-A9 NITROSATED AND NITROSYLATED PHOSPHODIESTERASE INHIBITOR COMPOUNDS, COMPOSITIONS AND THEIR USES 1998-09-11 WO disclosed
WO-1998019672-A1 NITROSATED AND NITROSYLATED PHOSPHODIESTERASE INHIBITOR COMPOUNDS, COMPOSITIONS AND THEIR USES NITROMED INC. (US) 1998-05-14 WO disclosed
US-4062846-A CNS STIMULANTS, MUSCLE RELAXANT E. R. SQUIBB & SONS, INC. (US) 1977-12-13 US disclosed
US-3995042-A MUSCLE RELAXANTS, CENTRAL NERVOUS SYSTEM STIMULANTS E. R. SQUIBB & SONS, INC. (US) 1976-11-30 US disclosed
US-3966733-A CENTRAL NERVOUS SYSTEM STIMULANTS, MUSCLE RELAXANTS E. R. SQUIBB & SONS, INC. (US) 1976-06-29 US disclosed
US-3957799-A STIMULANTS, MUSCLE RELAXANTS E. R. SQUIBB & SONS, INC. (US) 1976-05-18 US disclosed
US-3946025-A MUSCLE RELAXANTS E. R. SQUIBB & SONS, INC. (US) 1976-03-23 US disclosed