Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22034215 | 0.91 | TYMP (0.31) | TYMP | |
| Pyridine SCHEMBL22034356 | 0.91 | TYMP (0.30) | TYMP | |
| Pyridine SCHEMBL22034362 | 0.91 | TYMP (0.34) | TYMP | |
| SCHEMBL18490321 | 0.88 | TYMP (0.39) | TYMP | |
| SCHEMBL20474396 | 0.88 | TYMP (0.39) | TYMP | |
| SCHEMBL22034199 | 0.88 | TYMP (0.35) | TYMP | |
| SCHEMBL20481856 | 0.84 | KDM4E (0.39) | TYMP | |
| SCHEMBL29881809 | 0.84 | KDM4E (0.39) | TYMP | |
| SCHEMBL18490413 | 0.84 | TYMP (0.37) | TYMP | |
| SCHEMBL22034268 | 0.83 | TYMP (0.31) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3891164-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | Merck Sharp & Dohme Corp. (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020117625-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2020-06-11 | — | — | WO | disclosed |