Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 11/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17304193 | 1.00 | TYMP (0.49) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL18490335 | 1.00 | TYMP (0.49) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL21305111 | 1.00 | TYMP (0.49) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL21161236 | 0.98 | TYMP (0.49) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL17304194 | 0.98 | TYMP (0.49) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL18992250 | 0.98 | TYMP (0.49) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL20481728 | 0.96 | TYMP (0.49) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL19493439 | 0.95 | TYMP (0.48) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL25436741 | 0.95 | TYMP (0.53) | TYMPTAS1R3TAS1R1KDM4EHPGD | |
| SCHEMBL17301046 | 0.94 | TYMP (0.42) | TYMPTAS1R3TAS1R1KDM4ENT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3891164-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | Merck Sharp & Dohme Corp. (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020117625-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2020-06-11 | — | — | WO | disclosed |