Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.37 |
| ▸ | KDR | P35968 | 5/20 | 0.37 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.30 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.30 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21823995 | 0.88 | CSF1R (0.42) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL22036854 | 0.87 | CSF1R (0.42) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL22036035 | 0.86 | MDM2 (0.36) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL22036509 | 0.86 | CSF1R (0.40) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL21824002 | 0.79 | CSF1R (0.36) | KDRFLT3CSF1RPDGFRAMDM2 | |
| SCHEMBL21980611 | 0.79 | CSF1R (0.39) | KDRFLT3CSF1RPDGFRAMDM2 | |
| SCHEMBL21980614 | 0.77 | CSF1R (0.39) | KDRFLT3CSF1RPDGFRA | |
| SCHEMBL22036855 | 0.76 | CSF1R (0.41) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL21824004 | 0.76 | CSF1R (0.57) | KDRFLT3CSF1RPDGFRA | |
| SCHEMBL30673534 | 0.76 | CSF1R (0.57) | KDRFLT3CSF1RPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130762-B2 | Azaaryl derivative, preparation method therefor, and application thereof for use in pharmacy | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2021-09-28 | — | — | US | disclosed |
| US-20200165254-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165254-A1 | AZAARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FOR USE IN PHARMACY | FAR1, CSF1R, CSF3R | FGFR1 1240/4885FGFR2 1829/4885FGFR4 1220/4885 |
| US-11130762-B2 | Azaaryl derivative, preparation method therefor, and application thereof for use in pharmacy | FAR1, CSF1R, CSF3R | FGFR1 1240/4885FGFR2 1829/4885FGFR4 1220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.