Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNRNP200 | O75643 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22036232 | 0.93 | SNRNP200 (0.56) | SNRNP200POLBMEN1KMT2AKDM4E | |
| SCHEMBL16229979 | 0.90 | SNRNP200 (0.57) | SNRNP200POLBMEN1KMT2AKDM4E | |
| SCHEMBL12076 | 0.88 | SNRNP200 (0.55) | SNRNP200POLBMEN1KMT2AKDM4E | |
| SCHEMBL6720997 | 0.72 | MAPT (0.61) | SNRNP200POLBMEN1KMT2AKDM4E | |
| SCHEMBL22523765 | 0.69 | SNRNP200 (0.88) | SNRNP200POLBMEN1KMT2AKDM4E | |
| SCHEMBL14680225 | 0.64 | KMT2A (0.54) | SNRNP200POLBMEN1KMT2AKDM4E | |
| SCHEMBL3503224 | 0.60 | PTP4A3 (0.74) | SNRNP200POLBMEN1KMT2AKDM4E | |
| SCHEMBL3503222 | 0.60 | PTP4A3 (0.74) | SNRNP200POLBMEN1KMT2AKDM4E | |
| SCHEMBL8292183 | 0.57 | KMT2A (0.58) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL8291148 | 0.56 | MAPT (0.55) | POLBMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2525790-B1 | METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS | AGIOS PHARMACEUTICALS INC (US) | 2020-05-27 | — | — | EP | disclosed |