Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22038218 | 0.92 | POLB (0.47) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL17986795 | 0.90 | POLB (0.47) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL17844159 | 0.84 | POLB (0.42) | POLBKMT2AMEN1LMNACNR1 | |
| SCHEMBL29431598 | 0.83 | POLB (0.52) | POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL14677239 | 0.83 | POLB (0.52) | POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL17858002 | 0.83 | POLB (0.41) | POLBKMT2AMEN1 | |
| SCHEMBL30122217 | 0.82 | POLB (0.42) | POLBCYP1A2 | |
| SCHEMBL20267583 | 0.82 | POLB (0.42) | POLBCYP1A2 | |
| SCHEMBL22036956 | 0.81 | POLB (0.41) | POLB | |
| SCHEMBL23971584 | 0.80 | POLB (0.50) | POLBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233851-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-27 | — | — | EP | disclosed |