SCHEMBL2204142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2210741	0.81	FGFR2 (0.47)	FGFR2KDRMEN1KMT2AALDH1A1
	SCHEMBL22407507	0.78	FGFR2 (0.46)	FGFR2PDGFRAKDR
	SCHEMBL2206780	0.77	FGFR2 (0.43)	FGFR2PDGFRAKDRMEN1KMT2A
	SCHEMBL2206991	0.77	FGFR2 (0.47)	FGFR2PDGFRAKDRMAPTRAB9A
	SCHEMBL22407508	0.76	CA1 (0.51)	FGFR2PDGFRAKDRLMNAHTT
	SCHEMBL2209836	0.75	MAPT (0.58)	FGFR2KDRMEN1KMT2AALDH1A1
	SCHEMBL2204168	0.75	MAPT (0.53)	FGFR2KDRMEN1KMT2AALDH1A1
	SCHEMBL3701368	0.75	YES1 (0.50)	FGFR2PDGFRAKDRTGFBR1
	SCHEMBL15663468	0.74	FGFR2 (0.44)	FGFR2PDGFRAKDRMAPTLMNA
	SCHEMBL2209759	0.74	FGFR2 (0.44)	FGFR2PDGFRAKDRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.