Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 19/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KIF5B | P33176 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239197 | 1.00 | RET (0.43) | RETJAK2FLT3HSD11B1KIF5B | |
| SCHEMBL22041795 | 1.00 | RET (0.43) | RETJAK2FLT3HSD11B1KIF5B | |
| SCHEMBL22041857 | 0.91 | RET (0.43) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL22041858 | 0.91 | RET (0.43) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL30239455 | 0.89 | RET (0.44) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL22041863 | 0.88 | RET (0.46) | RETJAK2FLT3HSD11B1KIF5B | |
| SCHEMBL22041865 | 0.88 | RET (0.46) | RETJAK2FLT3HSD11B1KIF5B | |
| SCHEMBL22041667 | 0.84 | RET (0.42) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL22041672 | 0.84 | RET (0.42) | RETJAK2FLT3KIF5BKDR | |
| SCHEMBL30239632 | 0.84 | RET (0.42) | RETJAK2FLT3KIF5BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114474-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 苏州信诺维医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |