SCHEMBL22042136

SCHEMBL22042136

CCOC(=O)C(=CN(C)C)CC=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.50
NPSR1 Q6W5P4 2/20 0.37
GLO1 Q04760 1/20 0.37
ALDH1A1 P00352 4/20 0.33
CYP2D6 P10635 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 5/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
TSHR P16473 1/20 0.32
LMNA P02545 2/20 0.32
HSD17B10 Q99714 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
CYP2C19 P33261 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15786135 0.82 CYP2C9 (0.55) CYP2C9NPSR1GLO1ALDH1A1CYP2D6
SCHEMBL1325598 0.82 CYP2C9 (0.55) CYP2C9NPSR1GLO1ALDH1A1CYP2D6
SCHEMBL6015034 0.82 CYP2C9 (0.55) CYP2C9NPSR1GLO1ALDH1A1CYP2D6
SCHEMBL5901415 0.79 CYP2C9 (0.51) CYP2C9NPSR1GLO1ALDH1A1CYP2D6
SCHEMBL5901419 0.79 CYP2C9 (0.51) CYP2C9NPSR1GLO1ALDH1A1CYP2D6
SCHEMBL5908360 0.76 CYP2C9 (0.49) CYP2C9NPSR1GLO1ALDH1A1SMN1; SMN2
SCHEMBL10609078 0.76 CYP2C9 (0.49) CYP2C9NPSR1GLO1ALDH1A1CYP2D6
SCHEMBL6218422 0.76 CYP2C9 (0.51) CYP2C9NPSR1GLO1ALDH1A1CYP2D6
SCHEMBL27743484 0.76 NPSR1 (0.38) CYP2C9NPSR1GLO1ALDH1A1CYP2D6
SCHEMBL6820603 0.76 CYP2C9 (0.51) CYP2C9NPSR1GLO1ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026936-A Diphenylethylene bactericide containing pyrazole ring and preparation method and application thereof 华南理工大学 2024-05-14 CN claimed
CN-118026936-A Diphenylethylene bactericide containing pyrazole ring and preparation method and application thereof 华南理工大学 2024-05-14 CN disclosed
CN-118027149-A Stilbene-cationic peptide conjugate self-assembled nanoparticle and preparation method and application thereof 华南理工大学 2024-05-14 CN disclosed
WO-2020114482-A1 ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND 中国科学院上海药物研究所 2020-06-11 WO disclosed