Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18789928 | 0.88 | MAPT (0.47) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL14679732 | 0.87 | MAPT (0.35) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL12187066 | 0.85 | MAPT (0.39) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL23256716 | 0.84 | MAPT (0.36) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL21420061 | 0.84 | MAPT (0.39) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL13699061 | 0.83 | MAPT (0.40) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL17640447 | 0.81 | MAPT (0.39) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL22995714 | 0.81 | MAPT (0.39) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL26372302 | 0.80 | EGFR (0.31) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL18903903 | 0.80 | MAPT (0.40) | MAPTALDH1A1HPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020109524-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |