SCHEMBL22046136

SCHEMBL22046136

CCCCCCCCCCCSCCC=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
FAAH O00519 6/20 0.52
TRPV1 Q8NER1 2/20 0.52
CES2 O00748 3/20 0.47
GMNN O75496 1/20 0.47
TP53 P04637 1/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
THRB P10828 1/20 0.47
CYP2C9 P11712 1/20 0.47
BLM P54132 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CA2 P00918 1/20 0.45
ADH1B P00325 2/20 0.43
ADH1C P00326 2/20 0.43
ADH1A P07327 2/20 0.43
ADH4 P08319 2/20 0.43
ADH7 P40394 2/20 0.43
EPHX1 P07099 1/20 0.43
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10771503 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL8897261 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL29191469 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL10772384 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL10775795 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL22046131 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL10771513 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL10772357 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL10777107 1.00 TSHR (0.58) TSHRFAAHTRPV1CES2GMNN
SCHEMBL10774489 0.98 TSHR (0.54) TSHRFAAHTRPV1CES2GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021112957-A1 ARYL BENZOFURANONE- STABILIZED POLYCARBONATE COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-10 WO disclosed
EP-3660074-B1 SULFUR-STABILIZED COPOLYCARBONATES AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECH BV (NL) 2021-05-26 EP disclosed
EP-3660074-A1 SULFUR-STABILIZED COPOLYCARBONATES AND ARTICLES FORMED THEREFROM SABIC Global Technologies B.V. (NL) 2020-06-03 EP disclosed