Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.75 |
| ▸ | CTSK | P43235 | 14/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22643134 | 0.95 | CTSC (0.76) | CTSCCTSK | |
| SCHEMBL16071113 | 0.86 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16071115 | 0.82 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16043035 | 0.81 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL29809223 | 0.81 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL22046335 | 0.80 | CTSC (0.46) | CTSCCTSK | |
| SCHEMBL22643414 | 0.79 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16064658 | 0.79 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL21013246 | 0.79 | CTSC (0.76) | CTSCCTSK | |
| SCHEMBL16064172 | 0.78 | CTSC (1.00) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970252-B1 | SUBSTITUTED 2-AZA-BICYCLO[2.2.2]OCTANE-3-CARBOXYLIC ACID (BENZYL-CYANO-METHYL)-AMIDES INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2020-06-03 | — | — | EP | disclosed |