Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.47 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960369 | 0.83 | HPGD (0.58) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL20307195 | 0.81 | KDM4E (0.58) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL16066238 | 0.81 | KDM4E (0.50) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL18872983 | 0.80 | KDM4E (0.59) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL19959755 | 0.79 | KDM4E (0.51) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL10346630 | 0.78 | KDM4E (0.61) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL37035230 | 0.78 | KDM4E (0.61) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL17168519 | 0.78 | KDM4E (0.57) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL20307194 | 0.78 | KDM4E (0.50) | KDM4EMAPTLMNAPOLBHSD17B10 | |
| SCHEMBL17168517 | 0.78 | KDM4E (0.50) | KDM4EMAPTLMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266779-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-06-03 | — | — | EP | disclosed |