Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRAT | O95237 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | GJA1 | P17302 | 1/20 | 0.62 |
| ▸ | GJB2 | P29033 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13890068 | 1.00 | LRAT (0.66) | LRATALOX15KDM4ETSHRMEN1 | |
| SCHEMBL17323661 | 1.00 | LRAT (0.66) | LRATALOX15KDM4ETSHRMEN1 | |
| SCHEMBL13873415 | 1.00 | LRAT (0.66) | LRATALOX15KDM4ETSHRMEN1 | |
| SCHEMBL19619213 | 1.00 | LRAT (0.66) | LRATALOX15KDM4ETSHRMEN1 | |
| SCHEMBL16882180 | 1.00 | LRAT (0.66) | LRATALOX15KDM4ETSHRMEN1 | |
| SCHEMBL29593928 | 0.91 | TSHR (0.74) | LRATALOX15KDM4ETSHRMEN1 | |
| SCHEMBL9612084 | 0.91 | TSHR (0.74) | LRATALOX15KDM4ETSHRMEN1 | |
| SCHEMBL29885390 | 0.91 | TSHR (0.74) | LRATALOX15KDM4ETSHRMEN1 | |
| SCHEMBL17881390 | 0.91 | TSHR (0.74) | LRATALOX15KDM4ETSHRMEN1 | |
| Paromamine SCHEMBL14495298 | 0.91 | LRAT (0.79) | LRATALOX15KDM4ETSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113124-A1 | METHODS, COMPOSITIONS, AND KITS FOR TREATING OCULAR DISEASES | ELOXX PHARMACEUTICALS (US) | 2020-06-04 | — | — | WO | disclosed |