Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | UBE2M | P61081 | 10/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 10/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533470 | 0.86 | KMT2A (0.77) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL5637621 | 0.83 | KMT2A (0.73) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL1744058 | 0.83 | KMT2A (0.73) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL28919884 | 0.81 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL816962 | 0.81 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL30702394 | 0.81 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL1588423 | 0.80 | KMT2A (0.69) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL2710382 | 0.79 | KMT2A (1.00) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL7704275 | 0.79 | KMT2A (0.67) | KMT2AMEN1ALDH1A1TP53UBE2M | |
| SCHEMBL28919883 | 0.79 | KMT2A (0.67) | KMT2AMEN1ALDH1A1TP53UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712490-A | Amino-substituted pyridone derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2020-09-25 | — | — | CN | disclosed |
| WO-2020108579-A1 | AMINO-SUBSTITUTED PYRIDONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |