SCHEMBL2204866

SCHEMBL2204866

COc1nc(Nc2ccccc2)nc(Nc2ccc(C=Cc3ccc(Nc4nc(OC)nc(OC)n4)cc3S(=O)(=O)O)c(S(=O)(=O)O)c2)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA9 Q16790 3/20 0.48
MAPT P10636 3/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KDR P35968 1/20 0.45
LMNA P02545 2/20 0.44
ENPP2 Q13822 1/20 0.44
MAPK1 P28482 1/20 0.44
GAA P10253 1/20 0.43
ALDH1A1 P00352 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KCNH3 Q9ULD8 2/20 0.40
SNCA P37840 1/20 0.40
RHOA P61586 1/20 0.40
RAB9A P51151 1/20 0.39
CA12 O43570 1/20 0.39
TNNI3 P19429 1/20 0.39
TNNT2 P45379 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL2217024 0.99 CA1 (0.47) CA1CA2CA9MAPTHTT
SCHEMBL2221122 0.99 CA1 (0.50) CA1CA2CA9MAPTHTT
SCHEMBL2205677 0.99 CA1 (0.46) CA1CA2CA9MAPTHTT
SCHEMBL31310170 0.99 CA1 (0.46) CA1CA2CA9MAPTHTT
SCHEMBL8649081 0.99 CA1 (0.46) CA1CA2CA9MAPTHTT
SCHEMBL30855382 0.99 CA1 (0.46) CA1CA2CA9MAPTHTT
SCHEMBL8411089 0.98 CA1 (0.45) CA1CA2CA9MAPTHTT
SCHEMBL11619844 0.98 CA1 (0.45) CA1CA2CA9MAPTHTT
SCHEMBL8411116 0.98 CA1 (0.48) CA1CA2CA9MAPTHTT
SCHEMBL11400721 0.94 CA1 (0.42) CA1CA2CA9MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2716466-B1 THERMAL RECORDING MATERIAL CONTAINING STILBENE DISULPHONIC ACID FLUORESCENT WHITENING AGENT RICOH IND FRANCE SAS (FR) 2016-09-14 EP disclosed
EP-2722190-B1 Optimized undercoat for thermal recording material RICOH IND FRANCE SAS (FR) 2015-12-16 EP disclosed
EP-2722190-A1 Optimized undercoat for thermal recording material Ricoh Industrie France SAS (FR) 2014-04-23 EP disclosed
US-8546300-B2 Thermosensitive recording material and image recording method RICOH COMPANY, LTD. (JP) 2013-10-01 US disclosed
EP-2345541-B1 Thermosensitive recording material and image recording method RICOH CO LTD (JP) 2012-08-29 EP disclosed
US-20110177941-A1 THERMOSENSITIVE RECORDING MATERIAL AND IMAGE RECORDING METHOD RICOH COMPANY, LTD. (JP) 2011-07-21 US disclosed
EP-2345541-A2 Thermosensitive recording material and image recording method Ricoh Company, Ltd. (JP) 2011-07-20 EP disclosed