Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050504 | 0.86 | GAA (0.43) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL22051357 | 0.80 | MAPT (0.42) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL22051956 | 0.76 | MAPT (0.45) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL22050825 | 0.75 | MAPT (0.50) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL24212087 | 0.72 | GRIN2B (0.43) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL22050495 | 0.71 | GAA (0.44) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL21749683 | 0.71 | GAA (0.46) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL23877961 | 0.71 | GAA (0.45) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL22050826 | 0.70 | GAA (0.45) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL22050836 | 0.70 | KMT2A (0.42) | KMT2AMEN1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |