Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 10/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547345 | 0.88 | CYP1A2 (0.48) | GAAARALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL547834 | 0.88 | CYP1A2 (0.44) | GAAARALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL17117380 | 0.87 | GAA (0.47) | GAAARALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL17791499 | 0.83 | CYP1A2 (0.39) | GAAARALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL19129032 | 0.81 | GAA (0.38) | GAAARALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL16868371 | 0.81 | AR (0.42) | GAAARALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL16174758 | 0.81 | CYP1A2 (0.42) | GAAARUSP30ALDH1A1SMN1; SMN2 | |
| SCHEMBL17744910 | 0.77 | CYP1A2 (0.43) | GAAARALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL16182384 | 0.76 | CYP1A2 (0.47) | GAAALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL13267369 | 0.75 | CYP1A2 (0.46) | GAAALDH1A1SMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739069-B2 | Modulators of resistant androgen receptor | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2023-08-29 | — | — | US | disclosed |
| US-20200172504-A1 | MODULATORS OF RESISTANT ANDROGEN RECEPTOR | MEMORIAL SLOAN-KETTERING CANCER CENTER | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739069-B2 | Modulators of resistant androgen receptor | AR, NR5A1, ESRRA | GAA 4761/4885AR 1/4885USP30 1860/4885 |
| US-20200172504-A1 | MODULATORS OF RESISTANT ANDROGEN RECEPTOR | AR, NR5A1, ESRRA | GAA 4761/4885AR 1/4885USP30 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.