SCHEMBL22058684

SCHEMBL22058684

O=C(OCC1CCC2OC2C1)C1CCC2O[C@@H]2C1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 3/20 0.35
PTPN1 P18031 3/20 0.35
PPP1CC P36873 3/20 0.35
TP53 P04637 2/20 0.31
CYP3A4 P08684 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
PMP22 Q01453 1/20 0.31
TFPI2 P48307 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12632740 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL14754909 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL24975 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL14366763 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL23862867 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL18314119 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL23615814 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL16274032 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL22701849 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4
SCHEMBL11981558 1.00 PPM1B (0.35) PPM1BPTPN1PPP1CCTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3660549-A1 OPTICAL COMPONENT AND METHOD FOR MANUFACTURING SAME Daicel Corporation (JP) 2020-06-03 EP disclosed