SCHEMBL22058698

SCHEMBL22058698

COc1cc2c3c(c4c(c2cc1Sc1ccccc1)-c1ccccc1C41CCCCCCC1)C=CC(c1ccc(OCCO)cc1)(c1ccc(N2CCOCC2)cc1)O3

nearest known ligand 0.30

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.30
PDPK1 O15530 1/20 0.30
JAK2 O60674 1/20 0.30
EGFR P00533 1/20 0.30
MARK3 P27448 1/20 0.30
MAPK8 P45983 1/20 0.30
GSK3B P49841 1/20 0.30
MARK2 Q7KZI7 1/20 0.30
AURKB Q96GD4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26230389 0.97
SCHEMBL24604981 0.94
SCHEMBL22945012 0.93
SCHEMBL22058709 0.93 AKT1 (0.32)
SCHEMBL25697397 0.91
SCHEMBL22058727 0.91
SCHEMBL25697307 0.90
SCHEMBL21503737 0.90
SCHEMBL22058706 0.89
SCHEMBL24678603 0.88 ATM (0.33) CHEK1PDPK1JAK2EGFRMARK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11066523-B2 Photochromic polyrotaxane compound and curable composition comprising the photochromic polyrotaxane compound TOKUYAMA CORPORATION (JP) 2021-07-20 US disclosed
US-20200172681-A1 PHOTOCHROMIC POLYROTAXANE COMPOUND AND CURABLE COMPOSITION COMPRISING THE PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORPORATION (JP) 2020-06-04 US disclosed