Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GMNN | O75496 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752696 | 1.00 | PTPN1 (1.00) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL11587837 | 0.84 | PTPN1 (0.72) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL29457006 | 0.83 | PTPN1 (0.71) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL5857951 | 0.83 | PTPN1 (0.71) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL3263720 | 0.83 | PTPN1 (0.69) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL11589676 | 0.82 | PTPN1 (0.70) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL11713079 | 0.82 | PTPN1 (0.69) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL30375866 | 0.82 | PTPN1 (0.69) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL1448941 | 0.82 | PTPN1 (0.69) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL4533438 | 0.80 | PTPN1 (0.67) | PTPN1NR4A1NR4A2NR4A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328356-A | Process for preparing esters of arylacetic acids from alpha-halo-alkylarylketones | MONTEDISON S.P.A. (IT) | 1982-05-04 | — | — | US | claimed |
| US-4028264-A | Polybutene composition containing halo-carbonyl additives and use thereof | STANDARD OIL COMPANY (INDIANA) (US) | 1977-06-07 | — | — | US | claimed |
| US-3953475-A | MALEIC ANHYDRIDE | STANDARD OIL COMPANY (US) | 1976-04-27 | — | — | US | claimed |
| JP-7159992-A | — | — | None | — | — | JP | disclosed |
| JP-8006251-A | — | — | None | — | — | JP | disclosed |
| WO-2025101004-A1 | 6-ARYL IMIDAZO[2,1-B]THI/OXAZOLE-2-CARBOXILIC ACID DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR TREATING ALZHEIMER'S DISEASE CONTAINING SAME AS ACTIVE INGREDIENT | 한양대학교 에리카산학협력단 | 2025-05-15 | — | — | WO | disclosed |
| CN-119780312-A | Pre-column derivatization method for detecting impurity hydrazine in carbidopa-containing drug by GC and GC detection method | 上海奥科达医药科技股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-11-28 | — | — | US | disclosed |
| US-11974988-B2 | Neuroprotective compositions and methods of using the same | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-05-07 | — | — | US | disclosed |
| CN-116298039-A | Method for rapidly determining content of L-carnosine, L-histidine and beta-alanine methyl ester hydrochloride | 华熙生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20210205275-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2021-07-08 | — | — | US | disclosed |
| US-4275071-A | Imidazole derivatives | RECORDATI S.A. (CH) | 1981-06-23 | — | — | US | disclosed |
| EP-0001926-B1 | 1-(NAPHTHYLETHYL)IMIDAZOLE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1981-04-29 | — | — | EP | disclosed |
| EP-0013786-A1 | Imidazole derivatives, pharmaceutical compositions containing them and their preparation | SYNTEX (U.S.A.) INC. (US) | 1980-08-06 | — | — | EP | disclosed |
| US-4172141-A | ANTICONVULSANT, ANTISECRETORY, BACTERICIDE, FUNGICIDE, ANTIPROTOZOA | SYNTEX (U.S.A.) INC. (US) | 1979-10-23 | — | — | US | disclosed |
| EP-0001926-A1 | 1-(Naphthylethyl)imidazole derivatives, their preparation, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1979-05-16 | — | — | EP | disclosed |
| US-4150153-A | ANTICONVULSANTS, GASTRIC ANTISECRETORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4124767-A | Imidazolyl-oxime ethers having anti-mycotic and bactericidal activity | SIEGFRIED A.G. (CH) | 1978-11-07 | — | — | US | disclosed |
| US-4028264-A | Polybutene composition containing halo-carbonyl additives and use thereof | STANDARD OIL COMPANY (INDIANA) (US) | 1977-06-07 | — | — | US | disclosed |
| US-3953475-A | MALEIC ANHYDRIDE | STANDARD OIL COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205275-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | GAP43, NLN, SMN1; SMN2 | PTPN1 4457/4885NR4A1 3955/4885NR4A2 2679/4885 |
| US-11974988-B2 | Neuroprotective compositions and methods of using the same | GAP43, NLN, SMN1; SMN2 | PTPN1 4457/4885NR4A1 3955/4885NR4A2 2679/4885 |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | GAP43, NLN, SMN1; SMN2 | PTPN1 4457/4885NR4A1 3955/4885NR4A2 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.