Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 13/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TTBK1 | Q5TCY1 | 6/20 | 0.44 |
| ▸ | TTBK2 | Q6IQ55 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30662572 | 0.99 | MKNK1 (0.53) | MKNK1EGFRTTBK1TTBK2 | |
| SCHEMBL22061122 | 0.98 | MKNK1 (0.54) | MKNK1EGFRTTBK1TTBK2 | |
| Hydrochloric Acid SCHEMBL30662605 | 0.97 | MKNK1 (0.53) | MKNK1EGFRTTBK1TTBK2 | |
| SCHEMBL22060794 | 0.88 | MKNK1 (0.59) | MKNK1TTBK1TTBK2 | |
| Hydrochloric Acid SCHEMBL30662591 | 0.87 | MKNK1 (0.58) | MKNK1TTBK1TTBK2 | |
| SCHEMBL22061125 | 0.84 | MKNK1 (0.45) | MKNK1EGFRTTBK1TTBK2 | |
| SCHEMBL22061389 | 0.83 | MKNK1 (0.43) | MKNK1EGFRTTBK1TTBK2 | |
| SCHEMBL22061534 | 0.83 | EGFR (0.44) | MKNK1EGFRTTBK1TTBK2 | |
| SCHEMBL22060801 | 0.80 | EGFR (0.47) | MKNK1EGFRTTBK1TTBK2 | |
| SCHEMBL22061124 | 0.79 | MKNK1 (0.56) | MKNK1TTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108619-A1 | MNK INHIBITOR | 上海迪诺医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |