Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 8/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734905 | 1.00 | KLK7 (0.46) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734819 | 0.92 | KLK7 (0.38) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734890 | 0.90 | KLK7 (0.48) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734889 | 0.90 | KLK7 (0.48) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734811 | 0.88 | KLK7 (0.49) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734893 | 0.88 | KLK7 (0.49) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734886 | 0.87 | KLK7 (0.48) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL20734932 | 0.86 | KLK7 (0.36) | KLK7KLK5YAP1KMT2AGHSR | |
| SCHEMBL20734924 | 0.86 | KLK7 (0.36) | KLK7KLK5YAP1KMT2AGHSR | |
| SCHEMBL20734906 | 0.85 | KLK7 (0.47) | KLK7KLK5PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332440-B2 | 4-oxo-alkylated tetramic acid compound, and preparation method thereof | BEIJING JOEKAI BIOTECH. LLC (CN) | 2022-05-17 | — | — | US | disclosed |
| US-20200181081-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND, AND PREPARATION METHOD THEREOF | BEIJING JOEKAI BIOTECH. LLC (CN) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332440-B2 | 4-oxo-alkylated tetramic acid compound, and preparation method thereof | PSEN1, PSEN2, APP | KLK7 4215/4885KLK5 3322/4885PRSS1 4332/4885 |
| US-20200181081-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND, AND PREPARATION METHOD THEREOF | PSEN1, PSEN2, APP | KLK7 4215/4885KLK5 3322/4885PRSS1 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.