Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | IL17A | Q16552 | 1/20 | 0.49 |
| ▸ | BRD1 | O95696 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121739 | 0.88 | BRD4 (0.62) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30434840 | 0.88 | BRD4 (0.62) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL121574 | 0.84 | BRD4 (0.51) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30435329 | 0.84 | BRD4 (0.51) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30052713 | 0.84 | BRD4 (0.72) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL148581 | 0.84 | BRD4 (0.72) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL121626 | 0.78 | BRD4 (0.67) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30434474 | 0.78 | BRD4 (0.67) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL18045266 | 0.78 | BRD4 (0.72) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL120806 | 0.78 | BRD4 (0.64) | BRD4HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431086-B1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP (CA) | 2020-06-17 | — | — | EP | disclosed |