SCHEMBL22070485

SCHEMBL22070485

COC(=O)Cc1cccc(CCCOc2ccc(-c3ccn[nH]3)nc2)c1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CYP4F2 P78329 20/20 0.80
▸ CYP4A11 Q02928 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22070893 0.91 CYP4F2 (0.79) CYP4F2CYP4A11
SCHEMBL22071015 0.89 CYP4F2 (1.00) CYP4F2CYP4A11
SCHEMBL22071105 0.85 CYP4F2 (0.80) CYP4F2CYP4A11
SCHEMBL23309390 0.85 CYP4F2 (1.00) CYP4F2CYP4A11
SCHEMBL22098292 0.85 CYP4F2 (1.00) CYP4F2CYP4A11
SCHEMBL22071033 0.85 CYP4F2 (1.00) CYP4F2CYP4A11
SCHEMBL22070713 0.84 CYP4F2 (0.77) CYP4F2CYP4A11
SCHEMBL23309168 0.82 CYP4F2 (1.00) CYP4F2CYP4A11
SCHEMBL22098248 0.82 CYP4F2 (1.00) CYP4F2CYP4A11
SCHEMBL22070971 0.82 CYP4F2 (1.00) CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365192-B2 Pyridine compound substituted with azole TAISHO PHARMACEUTICAL CO., LTD. (JP) 2022-06-21 — — US disclosed
US-20210122741-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE TAISHO PHARMACEUTICAL CO., LTD (JP) 2021-04-29 — — US disclosed
EP-3666766-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE Taisho Pharmaceutical Co., Ltd. (JP) 2020-06-17 — — EP disclosed
CN-110914254-A Azole-substituted pyridine compound 大正制药株式会社 2020-03-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210122741-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE CYP2C19, CYP4A11, CYP11B1 CYP4F2 20/4885CYP4A11 2/4885
US-11365192-B2 Pyridine compound substituted with azole CYP2C19, CYP4A11, CYP11B1 CYP4F2 20/4885CYP4A11 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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