SCHEMBL22070646

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22070955	0.83	CYP1A2 (0.51)	CYP1A2MAPTSMN1; SMN2POLBGABRA2
	SCHEMBL6447808	0.83	SMN1; SMN2 (0.61)	CYP1A2MAPTSMN1; SMN2POLBGABRA2
	SCHEMBL10507044	0.79	CYP1A2 (0.68)	CYP1A2MAPTTRPM8SMN1; SMN2GABRA2
	SCHEMBL1996600	0.79	CYP4F2 (0.61)	MAPTSMN1; SMN2POLBALDH1A1CYP4F2
	SCHEMBL20730226	0.79	CYP1A2 (0.59)	CYP1A2MAPTCDC7DBF4TRPM8
	SCHEMBL6432573	0.79	MAPT (0.65)	CYP1A2MAPTALDH1A1
	SCHEMBL8258783	0.78	CYP1A2 (0.62)	CYP1A2MAPTTRPM8POLBGABRA2
	SCHEMBL2835370	0.78	CYP1A2 (0.66)	CYP1A2MAPTPOLBGABRA2GABRB2
	SCHEMBL22939583	0.76	CYP1A2 (0.59)	CYP1A2MAPTSMN1; SMN2POLBGABRA2
	SCHEMBL1478915	0.76	CYP1A2 (1.00)	CYP1A2MAPTSMN1; SMN2POLBGABRA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.