Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TST | Q16762 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | HAT1 | O14929 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22071696 | 0.91 | KDM4E (0.40) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL22071697 | 0.91 | MEN1 (0.42) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL22071728 | 0.90 | MEN1 (0.50) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL22071727 | 0.89 | MEN1 (0.41) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL22072088 | 0.87 | POLB (0.38) | KDM4ECASP1HSD17B10HTTMAPT | |
| SCHEMBL22071698 | 0.86 | MEN1 (0.41) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL22071699 | 0.81 | MEN1 (0.48) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL22072087 | 0.80 | POLB (0.43) | KDM4EHSD17B10HTTMAPTLMNA | |
| SCHEMBL22071751 | 0.80 | CYP3A4 (0.53) | KDM4EMEN1USP2CASP1BRCA1 | |
| SCHEMBL22071741 | 0.78 | POLB (0.54) | KDM4EHSD17B10HTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117974-A1 | COMPOUNDS AND COMPOSITIONS FOR EYE TREATMENTS | AVEDRO, INC. (US) | 2020-06-11 | — | — | WO | disclosed |