Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TST | Q16762 | 2/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HAT1 | O14929 | 3/20 | 0.42 |
| ▸ | RBBP7 | Q16576 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22071701 | 0.90 | USP2 (0.44) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22071722 | 0.88 | KDM4E (0.45) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22071681 | 0.83 | USP2 (0.56) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22071673 | 0.83 | USP2 (0.56) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22071725 | 0.83 | MEN1 (0.52) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22071726 | 0.83 | USP2 (0.45) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22071699 | 0.81 | MEN1 (0.48) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22072072 | 0.79 | MEN1 (0.46) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22071697 | 0.77 | MEN1 (0.42) | ESR1NR3C1ADRB2HTR2CADRA1A | |
| SCHEMBL22071721 | 0.76 | KDM4E (0.47) | ESR1NR3C1ADRB2HTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117974-A1 | COMPOUNDS AND COMPOSITIONS FOR EYE TREATMENTS | AVEDRO, INC. (US) | 2020-06-11 | — | — | WO | disclosed |