Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | USP2 | O75604 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HAT1 | O14929 | 3/20 | 0.53 |
| ▸ | RBBP7 | Q16576 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TST | Q16762 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22071680 | 0.92 | MEN1 (0.55) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL22071669 | 0.92 | MEN1 (0.55) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL22071725 | 0.90 | MEN1 (0.52) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL22071681 | 0.89 | USP2 (0.56) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL22071673 | 0.89 | USP2 (0.56) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL22071682 | 0.86 | KMT2A (0.58) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL22071670 | 0.86 | KMT2A (0.58) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL30621225 | 0.86 | KMT2A (0.58) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL22071679 | 0.85 | MEN1 (0.59) | MEN1KMT2AUSP2KDM4EMAPT | |
| SCHEMBL16239990 | 0.85 | MEN1 (0.59) | MEN1KMT2AUSP2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117974-A1 | COMPOUNDS AND COMPOSITIONS FOR EYE TREATMENTS | AVEDRO, INC. (US) | 2020-06-11 | — | — | WO | disclosed |