Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831233 | 0.92 | ATM (0.64) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL28423431 | 0.90 | ATM (0.61) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL1527050 | 0.87 | ATM (0.64) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL27619590 | 0.86 | ATM (0.76) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL8419741 | 0.84 | ATM (0.61) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL11750449 | 0.84 | HCAR2 (0.76) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL8417409 | 0.84 | HCAR2 (0.76) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL9150197 | 0.84 | HCAR2 (0.76) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL15921262 | 0.84 | HCAR2 (0.76) | ATMHCAR2MAPTNPSR1RAB9A | |
| SCHEMBL5831231 | 0.84 | HCAR2 (0.72) | ATMHCAR2MAPTNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020118178-A1 | MONOMETHYL FUMARATE-CARRIER CONJUGATES AND METHODS OF THEIR USE | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-06-11 | — | — | WO | disclosed |