Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 3/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775948 | 0.94 | NT5E (0.48) | NT5ETACR2TNFTSHRSSTR1 | |
| SCHEMBL1775945 | 0.94 | NT5E (0.48) | NT5ETACR2TNFTSHRSSTR1 | |
| SCHEMBL22073055 | 0.94 | TSHR (0.50) | NT5ETACR2TSHRLMNAPTPN1 | |
| SCHEMBL8225871 | 0.90 | NT5E (0.51) | NT5ETACR2TSHRSSTR1SSTR2 | |
| SCHEMBL2482599 | 0.90 | NT5E (0.51) | NT5ETACR2TSHRSSTR1SSTR2 | |
| SCHEMBL18241576 | 0.90 | NT5E (0.51) | NT5ETACR2TSHRSSTR1SSTR2 | |
| SCHEMBL18744567 | 0.90 | NT5E (0.51) | NT5ETACR2TSHRSSTR1SSTR2 | |
| SCHEMBL4181388 | 0.90 | NT5E (0.51) | NT5ETACR2TSHRSSTR1SSTR2 | |
| SCHEMBL19731824 | 0.90 | NT5E (0.51) | NT5ETACR2TSHRSSTR1SSTR2 | |
| SCHEMBL20295300 | 0.90 | NT5E (0.51) | NT5ETACR2TSHRSSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114418-A1 | ANTICOAGULANT PENTASACCHARIDE COMPOUND, COMPOSITION, AND PREPARATION METHOD AND MEDICAL USE THEREOF | 南京正大天晴制药有限公司 | 2020-06-11 | — | — | WO | disclosed |