Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207701 | 1.00 | MEN1 (0.40) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL2206548 | 0.90 | KMT2A (0.42) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL2206545 | 0.90 | KMT2A (0.42) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL2203741 | 0.87 | KCNH2 (0.46) | — | |
| SCHEMBL2203747 | 0.87 | KCNH2 (0.46) | — | |
| SCHEMBL2204406 | 0.83 | MAPT (0.40) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL2204404 | 0.83 | MAPT (0.40) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL2201849 | 0.82 | MEN1 (0.40) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL2201851 | 0.82 | MEN1 (0.40) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL2201993 | 0.80 | POLB (0.41) | MEN1KMT2APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981886-B2 | Antibiotics derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-07-19 | — | — | US | claimed |
| US-20080280888-A1 | Antibiotics Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-11-13 | — | — | US | claimed |
| US-7981886-B2 | Antibiotics derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-07-19 | — | — | US | disclosed |
| US-20080280888-A1 | Antibiotics Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280888-A1 | Antibiotics Derivatives | NR4A1, NR2C2, NR4A3 | MEN1 265/4885KMT2A 1756/4885POLB 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.