Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22077189 | 0.85 | S1PR1 (0.44) | S1PR1S1PR4S1PR5S1PR3ADORA3 | |
| SCHEMBL23916245 | 0.76 | KMT2A (0.37) | — | |
| SCHEMBL22074067 | 0.72 | S1PR1 (0.53) | S1PR1S1PR4S1PR5S1PR3ADORA3 | |
| SCHEMBL22074468 | 0.72 | S1PR1 (0.46) | S1PR1S1PR4S1PR5S1PR3ADORA3 | |
| SCHEMBL22074430 | 0.72 | S1PR1 (0.54) | S1PR1S1PR4S1PR5S1PR3ADORA3 | |
| SCHEMBL22077711 | 0.71 | S1PR1 (0.49) | S1PR1S1PR4S1PR5S1PR3ADORA3 | |
| SCHEMBL22077842 | 0.71 | S1PR1 (0.46) | S1PR1S1PR4S1PR5S1PR3ADORA3 | |
| SCHEMBL22074496 | 0.70 | S1PR1 (0.52) | S1PR1S1PR4S1PR5S1PR3ADORA3 | |
| SCHEMBL22074080 | 0.70 | S1PR1 (0.54) | S1PR1S1PR4S1PR5S1PR3ADORA3 | |
| SCHEMBL24201480 | 0.70 | S1PR1 (0.48) | S1PR1S1PR4S1PR5S1PR3ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892616-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020114475-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | 上海济煜医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |