Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | PREP | P48147 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12842007 | 0.87 | CHRM2 (0.51) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL13964499 | 0.87 | CHRM2 (0.51) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL12526945 | 0.87 | CHRM2 (0.51) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL22054238 | 0.81 | CHRM2 (0.62) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL25942989 | 0.81 | CHRM2 (0.62) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL24716574 | 0.80 | CHRM2 (0.50) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL25892541 | 0.80 | CHRM2 (0.45) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL5100405 | 0.79 | CHRM2 (0.68) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL14098541 | 0.79 | CHRM2 (0.68) | CHRM2CHRM1CHRM3HSD11B1PREP | |
| SCHEMBL5100393 | 0.79 | CHRM2 (0.68) | CHRM2CHRM1CHRM3HSD11B1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115506-A1 | QUINOLINONE AND BENZOXAZINE DERIVATIVES AS MUSCARINIC M1 AND/OR M4 RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-06-11 | — | — | WO | disclosed |