Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22077731 | 0.93 | S1PR1 (0.59) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22074444 | 0.92 | S1PR1 (0.57) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22077159 | 0.91 | S1PR1 (0.63) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22077716 | 0.89 | S1PR1 (0.55) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL25715612 | 0.87 | S1PR1 (0.57) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22077739 | 0.85 | S1PR1 (0.51) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22077203 | 0.84 | S1PR1 (0.66) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22074430 | 0.84 | S1PR1 (0.54) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL22077168 | 0.84 | S1PR1 (0.64) | S1PR1S1PR4S1PR5ADORA3S1PR2 | |
| SCHEMBL25904640 | 0.84 | S1PR1 (0.59) | S1PR1S1PR4S1PR5ADORA3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114475-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | 上海济煜医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |