SCHEMBL2207872

SCHEMBL2207872

CC(C)[Si](OC1C(=O)NC1C=C(F)F)(C(C)C)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12432942 1.00
SCHEMBL8173750 0.78
SCHEMBL8173746 0.78
SCHEMBL4189103 0.70
SCHEMBL8952552 0.70 PTPN1 (0.36)
SCHEMBL8952553 0.70 PTPN1 (0.36)
SCHEMBL4183138 0.69
SCHEMBL4183134 0.69
SCHEMBL4183133 0.69
SCHEMBL4172524 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7981926-B2 Fluorotaxoids RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2011-07-19 US disclosed
US-20090118355-A1 Fluorotaxoids RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2009-05-07 US disclosed
WO-2008021242-A2 FLUOROTAXOID-FATTY ACID CONJUGATES AND PHARMACEUTICAL COMPOSITIONS THEREOF THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-02-21 WO disclosed
WO-2007021957-A2 FLUOROTAXOIDS RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2007-02-22 WO disclosed