Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297528 | 0.89 | USP2 (0.44) | USP2SMN1; SMN2EPHX2TSHRALOX15 | |
| SCHEMBL16987094 | 0.87 | USP2 (0.45) | USP2SMN1; SMN2EPHX2TSHRALOX15 | |
| SCHEMBL31088801 | 0.86 | SMN1; SMN2 (0.40) | USP2SMN1; SMN2EPHX2TSHRALOX15 | |
| SCHEMBL17065177 | 0.82 | USP2 (0.46) | USP2SMN1; SMN2EPHX2TSHRALOX15 | |
| SCHEMBL2799150 | 0.82 | USP2 (0.43) | USP2SMN1; SMN2EPHX2EPHX1DDB1 | |
| SCHEMBL23070802 | 0.81 | USP2 (0.45) | USP2SMN1; SMN2EPHX2TSHRALOX15 | |
| SCHEMBL2442944 | 0.81 | USP2 (0.45) | USP2SMN1; SMN2EPHX2TSHRALOX15 | |
| SCHEMBL414000 | 0.81 | USP2 (0.45) | USP2SMN1; SMN2EPHX2TSHRALOX15 | |
| SCHEMBL21388184 | 0.81 | USP2 (0.45) | USP2SMN1; SMN2EPHX2TSHRALOX15 | |
| SCHEMBL24752804 | 0.81 | USP2 (0.45) | USP2SMN1; SMN2CNR2EPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285875-B | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-111285875-A | Heterocyclic compound, application thereof and pharmaceutical composition containing same | 苏州信诺维医药科技有限公司 | 2020-06-16 | — | — | CN | disclosed |
| WO-2020114474-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 苏州信诺维医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |