Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.56 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24559514 | 1.00 | POLB (0.59) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL12963372 | 0.89 | POLB (0.60) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL22930658 | 0.87 | POLB (0.53) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL24538794 | 0.86 | POLB (0.77) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL29332913 | 0.85 | POLB (0.62) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL19062414 | 0.85 | POLB (0.58) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL21298916 | 0.84 | POLB (0.57) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL25766886 | 0.83 | P2RY1 (0.62) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL22352121 | 0.83 | POLB (0.54) | POLBP2RY1ENPP1P2RY2SRC | |
| SCHEMBL20763160 | 0.83 | POLB (0.54) | POLBP2RY1ENPP1P2RY2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117624-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2020-06-11 | — | — | WO | disclosed |