SCHEMBL2208045

SCHEMBL2208045

SC1=NC2=CCC=CC2=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22345140 0.98
SCHEMBL4539335 0.68
SCHEMBL6688803 0.66 PPARA (0.31)
SCHEMBL9344147 0.66
SCHEMBL635226 0.64
SCHEMBL10770316 0.61
SCHEMBL12798230 0.61
SCHEMBL6869661 0.58
SCHEMBL10772455 0.57
SCHEMBL11786643 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114815428-A Photochromic material 惠州市华阳光学技术有限公司 2022-07-29 CN claimed
US-11357790-B2 Sterile formulation comprising a stable phosphorothioate oligonucleotide GENE SIGNAL INTERNATIONAL SA (CH) 2022-06-14 US claimed
US-20190350963-A1 STERILE FORMULATION COMPRISING A STABLE PHOSPHOROTHIOATE OLIGONUCLEOTIDE GENE SIGNAL INTERNATIONAL SA (CH) 2019-11-21 US claimed
US-10052343-B1 Sterile formulation comprising a stable phosphorothioate oligonucleotide GENE SIGNAL INTERNATIONAL SA (CH) 2018-08-21 US claimed
US-20180221401-A1 Sterile Formulation Comprising a Stable Phosphorothioate Oligonucleotide LABORATOIRES KÔL (FR) 2018-08-09 US claimed
WO-2018141908-A1 STERILE FORMULATION COMPRISING A STABLE PHOSPHOROTHIOATE OLIGONUCLEOTIDE GENE SIGNAL INTERNATIONAL SA (CH) 2018-08-09 WO claimed
EP-3004064-B1 PHARMACEUTICAL COMPOSITIONS BASED ON PHOTOCHEMICALLY STABLE SILVER COMPLEXES, CHLOREXIDINE AND CATIONIC SURFACTANTS PAVIA FARM S R L (IT) 2017-11-01 EP claimed
WO-2017025471-A1 STERILE EMULSION COMPRISING A STABLE PHOSPHOROTHIOATE OLIGONUCLEOTIDE GENE SIGNAL INTERNATIONAL SA (CH) 2017-02-16 WO claimed
US-20170035693-A1 Sterile Emulsion Comprising a Stable Phosphorothioate Oligonucleotide GENE SIGNAL INTERNATIONAL SA (CH) 2017-02-09 US claimed
EP-3128007-A1 STERILE EMULSION COMPRISING A STABLE PHOSPHOROTHIOATE OLIGONUCLEOTIDE Gene Signal International SA (CH) 2017-02-08 EP claimed
EP-1411765-A4 ENHANCEMENT OF THE STABILITY OF OLIGONUCLEOTIDES COMPRISING PHOSPHOROTHIOATE LINKAGES BY ADDITION OF WATER-SOLUBLE ANTIOXIDANTS ISIS PHARMACEUTICALS INC (US) 2006-05-10 EP claimed
US-20050208528-A1 Enhancement of the stability of oligonucleotides comprising phosphorothioate linkages by addition of water-soluble antioxidants ISIS PHARMACEUTICALS, INC. (US) 2005-09-22 US claimed
EP-1411765-A1 ENHANCEMENT OF THE STABILITY OF OLIGONUCLEOTIDES COMPRISING PHOSPHOROTHIOATE LINKAGES BY ADDITION OF WATER-SOLUBLE ANTIOXIDANTS ISIS Pharmaceuticals, Inc. (US) 2004-04-28 EP claimed
US-20030096770-A1 Enhancement of the stability of oligonucleotides comprising phosphorothioate linkages by addition of water-soluble antioxidants ISIS PHARMACEUTICALS, INC. 2003-05-22 US claimed
WO-2003005822-A1 ENHANCEMENT OF THE STABILITY OF OLIGONUCLEOTIDES COMPRISING PHOSPHOROTHIOATE LINKAGES BY ADDITION OF WATER-SOLUBLE ANTIOXIDANTS ISIS PHARMACEUTICALS, INC. (US) 2003-01-23 WO claimed
CN-114815428-B Photochromic materials 惠州市华阳光学技术有限公司 2024-04-26 CN disclosed
CN-110520134-B Sterile formulations comprising stabilized phosphorothioate oligonucleotides 基因信号国际公司 2023-07-18 CN disclosed
WO-2000051993-A2 DIHETERO-SUBSTITUTED METALLOPROTEASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 2000-09-08 WO disclosed
EP-0911693-A1 Heat development image forming process, thermally decoloring image recording process and process for decoloring cyanine dye Fuji Photo Film Co., Ltd. (JP) 1999-04-28 EP disclosed
US-5691394-A PHOTOSENSITIVE COMPOSITION WITH SENSITIZING DYE OF UNSATURATED THIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1997-11-25 US disclosed