Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352304 | 0.84 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL28904441 | 0.84 | HTR2A (0.37) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL7352312 | 0.84 | SLC6A4 (0.37) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL9973633 | 0.82 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL9057558 | 0.82 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL299793 | 0.82 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL9055032 | 0.81 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL1048931 | 0.80 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL11802556 | 0.80 | HTR2A (0.40) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL24179519 | 0.79 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115190-A1 | NOVEL ANTIBACTERIAL 3\"-DERIVATIVES OF 4,6-DISUBSTITUTED 2,5-DIDEOXYSTREPTAMINE AMINOGLYCOSIDE ANTIBIOTICS | AGILEBIOTICS B.V. (NL) | 2020-06-11 | — | — | WO | disclosed |