Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22081852 | 0.88 | KMT2A (0.56) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL22082690 | 0.88 | KMT2A (0.47) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL22082793 | 0.88 | KMT2A (0.51) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL22081792 | 0.87 | KMT2A (0.57) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL22082684 | 0.86 | MEN1 (0.52) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL22082669 | 0.85 | KMT2A (0.45) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL22082756 | 0.85 | KMT2A (0.45) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL22082759 | 0.85 | KMT2A (0.44) | KMT2AMEN1ALDH1A1HTTTSHR | |
| SCHEMBL22081719 | 0.84 | KMT2A (0.52) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL22081673 | 0.83 | KMT2A (0.63) | KMT2AMEN1LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |