SCHEMBL2208337

SCHEMBL2208337

Oc1ccc2ccc(S)cc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
ESR1 P03372 7/20 0.54
ESR2 Q92731 7/20 0.54
CYP3A4 P08684 2/20 0.44
ALOX15 P16050 2/20 0.44
TSHR P16473 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ABL1 P00519 1/20 0.41
ABCB1 P08183 1/20 0.41
BCR P11274 1/20 0.41
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
HSD17B1 P14061 1/20 0.40
CYP2B6 P20813 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B2 P37059 1/20 0.40
F12 P00748 1/20 0.39
CA12 O43570 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL863838 0.92 CYP1A2 (0.56) CYP1A2ESR1ESR2CYP3A4ALOX15
SCHEMBL29358095 0.84 CYP1A2 (0.72) CYP1A2ESR1ESR2CYP3A4ALOX15
SCHEMBL17311956 0.84 CYP1A2 (0.72) CYP1A2ESR1ESR2CYP3A4ALOX15
SCHEMBL29711 0.84 CYP1A2 (0.72) CYP1A2ESR1ESR2CYP3A4ALOX15
SCHEMBL29540246 0.84 CYP1A2 (0.40) CYP1A2ESR1ESR2
SCHEMBL332436 0.84 CYP1A2 (0.40) CYP1A2ESR1ESR2
SCHEMBL10719214 0.81 CYP1A2 (0.68) CYP1A2ESR1ESR2CYP3A4ALOX15
SCHEMBL3451975 0.81 CYP1A2 (0.78) CYP1A2ESR1ESR2CYP3A4ALOX15
Potassium SCHEMBL10719229 0.81 CYP1A2 (0.68) CYP1A2ESR1ESR2CYP3A4ALOX15
Benzene SCHEMBL29067759 0.78 CYP1A2 (0.74) CYP1A2ESR1ESR2CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014004146-A1 SILICONE RUBBER EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-01-03 WO claimed
EP-3202849-B1 FLOWABILITY IMPROVER FOR POLYCARBONATE AND POLYARYLATE, POLYCARBONATE RESIN COMPOSITION, POLYARYLATE RESIN COMPOSITION, AND MOLDED ARTICLE THEREOF KANEKA CORP (JP) 2020-05-13 EP disclosed
EP-3395894-B1 RESIN COMPOSITION AND ADHESIVE SHEET KANEKA CORP (JP) 2020-04-15 EP disclosed
US-10619004-B2 Flowability enhancing agent for polycarbonate resin, method for producing said agent, polycarbonate resin composition and molded article thereof KANEKA CORPORATION (JP) 2020-04-14 US disclosed
US-20200062893-A1 FLOWABILITY ENHANCING AGENT FOR POLYCARBONATE RESIN, METHOD FOR PRODUCING SAID AGENT, POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF KANEKA CORPORATION (JP) 2020-02-27 US disclosed
US-20200040180-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF KANEKA CORPORATION (JP) 2020-02-06 US disclosed
US-20190119490-A1 RESIN COMPOSITION, MOULDED ARTICLE, AND PLATED MOULDED ARTICLE KANEKA CORPORATION (JP) 2019-04-25 US disclosed
EP-2824131-B1 THERMALLY CONDUCTIVE RESIN MOLDED ARTICLE AND METHOD FOR MANUFACTURING THERMALLY CONDUCTIVE RESIN MOLDED ARTICLE KANEKA CORP (JP) 2019-04-24 EP disclosed
US-10253178-B2 Flowability improver for polycarbonate and polyarylate, polycarbonate resin composition, polyarylate resin composition, and molded article thereof KANEKA CORPORATION (JP) 2019-04-09 US disclosed
EP-2348071-B1 HIGH THERMAL CONDUCTIVITY THERMOPLASTIC RESIN COMPOSITION AND THERMOPLASTIC RESIN KANEKA CORP (JP) 2019-02-13 EP disclosed
US-20090111049-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-30 US disclosed
US-20080286685-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-7179401-B2 Thermotropic liquid-crystalline polymer KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2007-02-20 US disclosed
EP-1462468-B1 LIQUID-CRYSTAL POLYESTER RESIN UENO SEIYAKU OYO KENKYUJO KK (JP) 2006-08-02 EP disclosed
EP-1422256-B1 THERMOTROPIC LIQUID-CRYSTAL POLYMER UENO SEIYAKU OYO KENKYUJO KK (JP) 2006-08-02 EP disclosed
US-6984712-B2 Liquid-crystal polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2006-01-10 US disclosed
US-20050054811-A1 Liquid-crystal polyester resin UENO FINE CHEMICALS INDUSTRY, LTD. (JP) 2005-03-10 US disclosed
US-20040256599-A1 Thermotorpic liquid-crystal polymer UENO FINE CHEMICALS INDUSTRY, LTD. (JP) 2004-12-23 US disclosed
EP-1462468-A1 LIQUID-CRYSTAL POLYESTER RESIN KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2004-09-29 EP disclosed
EP-1422256-A1 THERMOTROPIC LIQUID-CRYSTAL POLYMER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 2004-05-26 EP disclosed