Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533476 | 0.85 | HDAC6 (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29424838 | 0.85 | HDAC6 (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22084384 | 0.85 | DAPK1 (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22533785 | 0.84 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29424732 | 0.84 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29424867 | 0.81 | HPGD (0.56) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22533420 | 0.81 | HPGD (0.56) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22085120 | 0.80 | DAPK1 (0.42) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22085122 | 0.80 | FGFR1 (0.43) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22533518 | 0.77 | HDAC6 (0.41) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117938-A1 | PRODRUGS OF ANTI-CANCER AND ANTI-AUTOIMMUNE DISEASES THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-06-11 | — | — | WO | disclosed |