Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.46 |
| ▸ | MAOA | P21397 | 9/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617247 | 0.79 | MAOB (0.49) | MAOBMAOATOP1NPC1ALDH1A1 | |
| SCHEMBL22083876 | 0.77 | POLB (0.41) | MAOBMAOAARPDE3BPDE3A | |
| SCHEMBL26245640 | 0.74 | PDE3B (0.46) | PDE3BPDE3A | |
| SCHEMBL22083877 | 0.74 | PDE3B (0.43) | MAOBMAOAPDK2NPC1RAB9A | |
| SCHEMBL30317738 | 0.74 | MAOB (0.49) | MAOBMAOAALOX5MRGPRX4 | |
| SCHEMBL5266330 | 0.74 | MAOB (0.49) | MAOBMAOAALOX5MRGPRX4 | |
| SCHEMBL23915840 | 0.73 | S1PR1 (0.43) | — | |
| SCHEMBL22077171 | 0.73 | S1PR1 (0.36) | MAOBMAOAALDH1A1HPGD | |
| SCHEMBL22077867 | 0.72 | PDE3B (0.46) | PDE3BPDE3A | |
| SCHEMBL22077865 | 0.72 | PDE3B (0.46) | PDK2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114477-A1 | COMPOUND ACTING AS IMMUNOMODULATOR, PREPARATION METHOD THEREFOR AND USES THEREOF | 上海济煜医药科技有限公司 | 2020-06-11 | — | — | WO | disclosed |