SCHEMBL2208947

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2213345	0.92	GCK (0.59)	GCKRAB9ANPC1SMN1; SMN2ADORA2A
	SCHEMBL2664624	0.91	GCK (0.61)	GCKRAB9ANPC1L3MBTL1
	SCHEMBL2212669	0.90	GCK (0.57)	GCKRAB9ANPC1SMN1; SMN2ADORA2A
	SCHEMBL2642655	0.89	GCK (0.62)	GCKADORA2AL3MBTL1
	SCHEMBL2213370	0.89	GCK (0.73)	GCKRAB9ANPC1SMN1; SMN2L3MBTL1
	SCHEMBL2208913	0.89	GCK (0.62)	GCKRAB9ANPC1SMN1; SMN2L3MBTL1
	SCHEMBL2212557	0.89	GCK (0.73)	GCKRAB9ANPC1SMN1; SMN2L3MBTL1
	SCHEMBL2212679	0.88	GCK (0.75)	GCKL3MBTL1
	SCHEMBL2642911	0.88	GCK (0.75)	GCKRAB9ANPC1SMN1; SMN2LMNA
	SCHEMBL2208970	0.88	GCK (0.58)	GCKL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.