Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669331 | 0.82 | TLR8 (0.48) | KMT2AALDH1A1CYP1A2CYP2D6HTT | |
| SCHEMBL25171851 | 0.79 | CYP1A2 (0.59) | KMT2AS1PR1NPY5RBACE1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31258765 | 0.77 | CYP1A2 (0.57) | KMT2AS1PR1NPY5RBACE1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL25167011 | 0.77 | CYP1A2 (0.57) | KMT2AS1PR1NPY5RBACE1ALDH1A1 | |
| SCHEMBL3665285 | 0.77 | KMT2A (0.39) | KMT2AS1PR1NPY5RBACE1NPC1 | |
| SCHEMBL14336554 | 0.76 | S1PR1 (0.41) | KMT2AS1PR1NPY5RBACE1ALDH1A1 | |
| SCHEMBL13682821 | 0.76 | S1PR1 (0.41) | KMT2AS1PR1NPY5RPOLBCASP1 | |
| SCHEMBL9375371 | 0.76 | CCR1 (0.48) | ALDH1A1CYP2D6HTTKDM4ESMN1; SMN2 | |
| SCHEMBL9375374 | 0.74 | KDM4E (0.44) | KMT2AALDH1A1CYP1A2HTTKDM4E | |
| SCHEMBL2299818 | 0.74 | KMT2A (0.45) | KMT2ABACE1ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120694-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-18 | — | — | WO | disclosed |