SCHEMBL2209159

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3699715	0.92	POLB (0.52)	ENPP3POLBKDM4EUSP2PPARG
	SCHEMBL3707198	0.91	AURKA (0.51)	KDRENPP3POLBKDM4EUSP2
	SCHEMBL3703189	0.85	KDR (0.50)	KDRENPP3POLBKDM4EUSP2
	SCHEMBL3699216	0.84	MAPT (0.48)	ENPP3POLBKDM4EUSP2PPARG
	SCHEMBL2966793	0.84	KDR (0.51)	KDRENPP3POLBKDM4EMAPT
	SCHEMBL3700780	0.83	POLB (0.42)	KDRENPP3POLBKDM4EUSP2
	SCHEMBL3702833	0.83	KDR (0.50)	KDRENPP3POLBKDM4EMAPT
	SCHEMBL3703048	0.83	KDR (0.50)	KDRENPP3POLBMAPTLMNA
	SCHEMBL2210774	0.81	AURKA (0.49)	KDRENPP3POLBKDM4EMAPT
	SCHEMBL15663382	0.81	MAPT (0.54)	KDRENPP3MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.